Detection of trace concentrations of S-nitrosothiols by means of a capacitive sensor
نویسندگان
چکیده
Small molecule S-nitrosothiols are a class of endogenous chemicals in the body, which have been implicated in a variety of biological functions. However, the labile nature of NO and the limits of current detection assays have made studying these molecules difficult. Here we present a method for detecting trace concentrations of S-nitrosothiols in biological fluids. Capacitive sensors when coupled to a semiconducting material represent a method for detecting trace quantities of a chemical in complex solutions. We have taken advantage of the semiconducting and chemical properties of polydopamine to construct a capacitive sensor and associated method of use, which specifically senses S-nitrosothiols in complex biological solutions.
منابع مشابه
Design and Construction of a New Capacitive Tactile Sensor for Measuring Normal Tactile Force
This paper presents the design, construction and testing of a new capacitive tactile sensor for measurement of normal tactile force. The operation of proposed sensor has been investigated in ASTABLE and MONOSTABLE circuits. According to the results of these circuits the deviation of ASTABLE circuit results is less than MONOSTABLE circuit results. In addition, the results obtained from ASTABLE c...
متن کاملField detection of CO and CH4 by NIR 2f modulation laser spectroscopy
A novel compact fiber-coupled NIR system based on a DFB diode laser source is employed as a portable and sensitive gas sensor for trace detection of combustion pollutant molecules. We demonstrate the performance of such an NIR gas sensor by tracing the absorption lines of CO and CH4 using 2f-WMS technique at moderate temperature of T ~ 600°C in the recuperator channel of an industrial furnace...
متن کاملUultra-trace determination of cadmium (II) in aqueous environmental samples by a new ion selective electrode based on nefazodone and 1-butyl-3-methylimidazolium hexafluorophosphate ionic liquid
Background and Objective: Cadmium is a potential environmental contaminant that causes adverse effects on the environment and the health of living organisms. Therefore, designing a simple and economic technique for its determination is very important. In this respect, a potentiometric sensor based on nefazodone as the ionophore and [BMIM]PF6 as the ionic additive were developed for the determin...
متن کاملAnalytical Analysis of Capacitive Pressure Sensor with Clamped Diaphragm (RESEARCH NOTE)
Abstract In this paper analytical analysis of capacitive pressure sensor with clamped diaphragm is presented. Mechanical and electrical properties of the sensor are theoretically analyzed based on theory of thin plates with small deflection and the results are evaluated by use of finite element analysis. The central deflection and capacitance values under uniform external pressure are calcula...
متن کاملConstruction of a Carbon Paste Electrode Based on Novel Thiolated Ligand Capped Gold Nanoparticles for Determination of Trace Amounts of Mercury(II)
In the present study, a simple electrochemical sensor for trace determination of Hg(II) ions in aqueous solutions was introduced. The proposed sensor was designed by incorporation of the 4-methyl-piperidine-carbodithioate capped gold nanoparticles (GNPs) into the carbon paste electrode (CPE), which provides a remarkably improved sensitivity for stripping voltammetric determination of Hg(II). Di...
متن کامل